The SMART Genomics Advisor represents a first in terms of genomic integration into Electronic Health Records (EHRs) and Personal Health Records (PHRs). Its robustness and interoperability with a wide variety of systems is done through the SMART framework and allows clinicians to easily access relevant clinical and genomic information across a variety of EHR/PHRs. The application supports integration of clinical and genomic data from SMART-enabled service.
DBEMR is a clinical app built on the SMART Genomics platform targeted towards children's healthcare that is designed to synthesize a child's medical and genomic history and provide personalized medical recommendations and feedback to assist the primary physicians and caregivers.
SMART Precision Medicine displays population-level information about somatic cancer mutations relative to a single patient. For example, if a lung cancer patient has the EGFR exon 19 deletion, they and their clinician(s) might want to know how common EGFR mutations are compared to other gene mutations, and how often the exon 19 deletion is found compared to other variants. This allows for more personalized and effective medical treatment.
Variant Mapper demonstrates how genomics can be integrated into clinical decision support. Comparing patients' DNA variants and those from a database documenting genotype-phenotype assoction (in this case, Clinvar), this application alerts clinicians about potential risk factors. By the dynamically binding the knowledge database and patients' genotype, the application also allows its clinicians to learn more about their patients as the database grows.