@article {79741,
	title = {Olfactory cortical neurons read out a relative time code in the olfactory bulb},
	journal = {Nature Neuroscience},
	volume = {16},
	number = {7},
	year = {2013},
	pages = {949-957},
	abstract = {Odor stimulation evokes complex spatiotemporal activity in the olfactory bulb, suggesting that both the identity of activated neurons and the timing of their activity convey information about odors. However, whether and how downstream neurons decipher these temporal patterns remains unknown. We addressed this question by measuring the spiking activity of downstream neurons while optogenetically stimulating two foci in the olfactory bulb with varying relative timing in mice. We found that the overall spike rates of piriform cortex neurons (PCNs) were sensitive to the relative timing of activation. Posterior PCNs showed higher sensitivity to relative input times than neurons in the anterior piriform cortex. In contrast, olfactory bulb neurons rarely showed such sensitivity. Thus, the brain can transform a relative time code in the periphery into a firing rate{\textendash}based representation in central brain areas, providing evidence for the relevance of a relative time{\textendash}based code in the olfactory bulb.},
	url = {http://www.nature.com.ezp-prod1.hul.harvard.edu/neuro/journal/v16/n7/full/nn.3407.html},
	author = {R. Haddad and A. Lanjuin and L Madisen and H. Zeng and V.N. Murthy and N. Uchida}
}
