Alison Klein, M.H.S., Ph.D.
Johns Hopkins School of Medicine
Dr. Klein is the Director of the National Familial Pancreas Tumor Registry, the largest pancreatic cancer family registry in the world (www.nfptr.org). She is a genetic epidemiologist with a focus on cancer research. Her current work focuses on the identification the genetic and environmental risk factors for pancreatic cancer as well as other complex genetic diseases. In the first demonstration that whole exome sequencing approaches can be used to identify the causes of a hereditary disease, she discovered that mutations in the PALB2 gene increase the risk of pancreatic cancer. In addition, she has developed a clinical risk assessment tool for high-risk pancreatic cancer families, PancPRO in order to facilitate the translation of her research findings into the clinical setting.