Guo-Cheng Yuan (袁国丞), Ph.D.

Guo-Cheng Yuan (袁国丞), Ph.D.

Associate Professor at Harvard Chan School of Public Health and Dana-Farber Cancer Institute
Research Interests : Computational Biology, Gene Regulation, Single Cell Analysis, Cancer, Stem Cell, Developmental Biology
GCYuan
Dr. Guo-Cheng Yuan is an Associate Professor at Dana-Farber Cancer Institute/Harvard Chan School of Public Health and a Principal Faculty member at Harvard Stem Cell Institute. He obtained a PhD degree in Mathematics from University of Maryland, followed by postdoctoral training at Brown University. Dr. Yuan transitioned into a computational biologist by taking up a postdoctoral fellow position at Harvard University before joining Dana-Farber as a faculty member. Dr. Yuan’s group has developed a number of computational methods for analyzing and interpreting large-scale biological data. Notable examples include methods for annotating chromatin states from ChIPseq data (Haystack, diHMM), for identifying cell types and lineages from single-cell transcriptomic data (SCUBA, GiniClust), and for quantifying genome-editing outcomes from targeted CRISPR/Cas9 sequencing data (CRISPResso).  For over a decade, Dr. Yuan’s group has extensively collaborated with experimental biologists to elucidate the gene regulatory networks underlying cell state maintenance and transitions, and apply the knowledge to gain mechanistic insights into cancer and hematological diseases.

Contact Information

360 Longwood Ave, Boston, MA 02115
p: 617-582-8532