Zhe Li (李哲), Ph.D.

Zhe Li (李哲), Ph.D.

Associate Professor of Medicine at Harvard Medical School and Brigham & Women’s Hospital
Research Interests: Stem cell and cancer, cells of origin of cancer, developmental oncobiology, mouse models of cancer, breast cancer, prostate cancer, ovarian cancer
Lizhe
Zhe Li is currently an Associate Professor of Medicine at Harvard Medical School (HMS) and an Associate Geneticist at Brigham and Women’s Hospital (BWH). He received his Ph.D. in Molecular & Cellular Biology from Dartmouth College in 2003. After that, he performed postdoctoral training with Dr. Stuart Orkin at HMS and Boston Children’s Hospital. He joined BWH as a Principal Investigator in 2009. Research in the Li laboratory focuses on developmental oncobiology of epithelial cancers. The lab is particularly interested in elucidating how cells of origin contribute to the cancer phenotype, and what is the molecular and cellular basis leading to formation of cancer stem cells (CSCs, also known as tumor-initiating cells, or tumor-propagating cells) from normal target cells of cancer. The lab studies these by applying concepts and tools from stem cell biology and developmental biology, and by using a combination of mouse genetics, biochemistry, and genomic approaches. The long-term goal is to develop novel approaches to treat and/or to prevent cancer.

Contact Information

77 Avenue Louis Pasteur, NRB Room 458E, Boston, MA 02115
p: 617-525-4740