The idea of the SMART Genomics: Precision Cancer Medicine app is to display population-level information about somatic cancer mutations relative to a single patient. For example, if a lung cancer patient has the EGFR exon 19 deletion, they and their clinician(s) might want to know how common EGFR mutations are compared to other gene mutations, and how often the exon 19 deletion is found compared to other
Contribution to new book: Pathobiology of Cancer Regimen-Related Toxicities
Chapter Abstract: “The efficacy of chemotherapy depends on several different patient factors, including age, gender, ethnicity, and genetics. A patient’s genetic composition strongly influences how chemotherapeutic agents are absorbed, distributed, metabolized, and excreted by the body. Consequently, variations in genes that are responsible for these activities play a significant role in determining the prognostic outcome for patients. Studying and identifying these associated genes have been main foci of
This week, researchers at Harvard Medical School's Biomedical Cybernetics Laboratory released two free iPad applications, available on iTunes, intended to help clinicians assess diabetes risk and improve treatment compliance in patients with the disease.
Gil Alterovitz, an assistant professor at Harvard Medical School and the HMS Center for Biomedical Informatics, told BioInform that he and colleagues developed the apps to provide a standardized method of communicating clinical and genetic information to physicians, caregivers, and patients ...