Letter of Intent

To participate in the DTI Tractography challenge, please download and fill in the letter of intent for participation, and return it signed to After registration of your team, you will receive the link to access the workshop datasets.

DTI Challenge Datasets

The MICCAI 2015 DTI Challenge datasets consist of DWI, T1-weighted and T2-weighted anonymized scans acquired on four neurosurgical cases. The data include the segmentation of the tumor and edema regions. In addition, a set of regions-of-interest (ROIs) are provided as neuranatomical aid (optional) to help locate the pyramidal tract.

The neurosurgical datasets are available for download to the DTI Challenge participants on the XNAT Central website. The cases include neurosurgical data that were acquired in the AMIGO suite.

Clinical Goal

Tractography teams are invited to reconstruct the left and right pyramidal tract (PT) located in the peritumoral area. The PT starts in the cerebral cortex and terminates in the spinal cord. The tract courses through the posterior limb of the internal capsule, the cerebral peduncle, the ventral pons, the ventral surface of the medulla, and decussates in the lower medulla.

Tractography Methods

Tractography algorithms used by the DTI Challenge teams to reconstruct the clinical tract of interest from the neurosurgical cases can be novel tools or existing methods. There is no restriction on the choice of the algorithm. 


Participants are invited to submit a single zip archive file (less than 15 MB) containing the following elements for each clinical case:

  1. The left and right pyramidal tracts in vtkPolydata file format (VTK-ASCII) 
  2. The regions-of-interest (ROIs) used for the tractography reconstruction in Nrrd file format
  3. A png file showing a coronal view of the two sets of tracts overlaid on a FA image.

In addition, participants are required to submit a paper describing the methodology and results. The paper should include the following five elements:  (i) the  diffusion model, (ii) the fiber tracking algorithm (deterministic, probabilistic, filtered, global), (iii) the regions of interest, (iv) the tractography parameters used in each clinical case, and (v) a description of the tractography pipeline and software used. Participants are invited to propose an evaluation criteria for their tractography method in the Appendix of the paper.Supplementary materials such as short videos, are encouraged, but not mandatory. Papers should be formatted in Lecture Notes in Computer Science style. The file format for submission is Adobe Portable Document Format (PDF). Other formats will not be accepted.

Tractography results should be submitted with the following file naming convention:

  •  tracts: patientN_left_tract_TeamName.vtk, patientN_right_tract_TeamName.vtk (e.g. patient1_left_tract_TeamSmith.vtk, patient1_right_tract_TeamSmith.vtk)
  • regions of interest: patientN_left_ROI_TeamName.nrrd, patientN_right_ROI_TeamName.nrrd (e.g. patient1_left_ROI_TeamSmith.nrrd, patient1_right_ROI_TeamSmith.nrrd)
  • coronal view: patientN_coronal_view_LastName.png (e.g. patient1_coronal_view_TeamSmith.png)

All results should be in the original DWI image space. The zip archive should be named

Submission site

Participants are invited to upload their results and paper at A training dataset is available for download upon request.

Important Dates

Please note that the DTI Challenge submission site will be open until the following dates and times:  

Neurosurgical case #1: Preliminary results: June 23, 2015, 5 pm EST; Final results: June 30, 5 pm EST

Neurosurgical case #2: Preliminary results: July 10, 2015 EST (extended); Final results: July 15, 5 pm EST (extended). For case #2, participants are invited to submit the pyramidal tract, and the arcuate fasciculus (optional).

Neurosurgical case #3: Preliminary results: July 21, 2015, 5 pm EST (extended); Final results and paper submission: July 28, 5 pm EST (extended)

Participants are required to submit a sample tract for each neurosurgical case before the preliminary results deadline. The sample tract does not need to be anatomically accurate, and is intended to help anticipate and solve any file format compatibility issue prior to the final submission deadline. For questions related to the submission process and/or file format compatibility, please send an e-mail to

Letter of intent 2015 DTI Challenge 44 KB