Gaudet LabDepartment of Molecular and Cellular BiologyHarvard University
Our group studies the Nramp family of transition metal transporters, and recently determined this inward-facing structure
We study the evolution, structure and assembly of clustered protocadherins, which are involved in neuronal self avoidance.
Our recent BBA Biomembranes review highlights how these analyses are powerful tools in studies of membrane proteins
Our new structures illustrate the three principal conformations of an Nramp transporter.