Date:
Location:
12PM - 1PM | Talks@12: Next Big Things | TMEC Amphitheater |
1PM - 3PM |
Celebrating Innovation and Collaboration at HMS |
TMEC Atrium |
1:30PM - 2PM | Presentation by Dean Daley and Lightning Talks | TMEC Amphitheater |
Talks@12: Next Big Things
Moderator |
David Golan Dean for Research Operations and Global Programs |
Featured Speakers |
Richard Frank Margaret T. Morris Professor of Health Care Policy "Understanding the idiosyncratic performance of the generic pharaceutical market" |
Sloan Devlin Assistant Professor of Biological Chemistry and Molecular Pharmacology "Control of gut bacterial bile acid metabolism using small molecules" |
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Peter Sorger Otto Krayer Professor of Systems Pharmacology "The future of precision medicine" |
Celebrating Innovation and Collaboration at HMS
Featured Presentation |
George Q. Daley Dean of the Faculty of Medicine |
Poster Lightning Talks |
Fenna Krienen Postdoctoral Fellow, Dept. of Genetics "Evolutional novelties in primate brains revealed by single-cell RNA-seq" |
Krishna Padmanabha Das Research Fellow, Dept. of Biological Chemistry and Molecular Pharmacology "DNA-corralled nanodiscs for studies of large membrane |
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Katherine Redfield M.D. Candidate, Harvard-MIT Health Sciences and Technology "Engineering a novel approach to pancreatitis" |
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Lauren Orefice Assistant Professor of Genetics, HMS; Assistant Professor of Molecular Biology, MGH "Targeting peripheral somatosensory neurons to improve tactile and beahvioral phenotypes in ASD" |
Poster Showcase
- Charles Weitz, Alan Brown: "Cryo-EM analysis of a mammalian circadian clock complexes"
- Michael Springer: "Quantitative foldable viral detection; development of at home diagnostics"
- Sloan Devlin: "Small molecule inhibitor of gut bacterial bile salt hydrolases"
- Sloan Devlin, Jun Huh: "Immunomodulatory metabolites from gut bacteria and their role in inflammatory bowel diseases"
- Stephen Blacklow, Tomas Kirchausen: "New microscopy to study mechanisms of Notch signaling"
- Stephen Blacklow: "Structural reorgnization of SHP2 by oncogenic mutations and its potential for reversal by allosteric inhibitors"
- Donald Coen: "Development of new compounds that inhibit the human cytomegalovirus nuclear egress complex"
- David Knipe, Donald Coen: "Use of iPSC-derived sensory neurons for molecular studies of herpes simplex virus latent infection"
- Pamela Silver, Dennis Kasper: "Seeing in dark places: probing bacterial regulation in the mammalian gut using engineered living biosensors"
- Peter Park: "Antisense oligonucleotide-based ganulin augmentation therapy in neurodegenerative diseases"
- Pascal Kaeser, John Assad, Peng Yin: "Mechanisms and functions of rapid dopamine coding"
- Michael Greenberg: "Next-generation AAV therapies for the management of intractable chronic pain"
- Amy Wagers, Ya-Chieh Hsu, Diane Mathis: "Regulatory T cell control of stem/progenitor cells during tissue regeneration"
- David Corey: "Gene therapy for hereditary deafness"
- David Golan, Mihaela Gadjeva: "Inhibition of P. falciparum intra-erythrocytic development by ibudilast and ibudilast-like small molecules"
- Ifat Rubin-Bejerano: "The HMS Q-FASTR Program identifies, supports, and expedites translational research with commercialization potential"
- Tim Mitchison, Ifat Rubin-Bejerano, Catherine Dubreuil, Andrea Chen, Jeffrey Way: "I-Hub (Ideation Hub)"
- Caroline Shamu, Katrina Rudnicki, Andrea Chen: "Harvard Medical School Foundry"
- Peter Sorger, Laura Maliszewski, Florence Bourgeouis, Monica Ruse, Helen Yang: "Harvard-MIT Center for Regulatory Science Fellowship Program"
- Daniel Finley, Ying Lu: "Proteasome regulation and the ubiquitin code"
- Jan Drugowitsch, Rachel Wilson: "Neural correlates of uncertainty"
- Adrian Salic: "PKD-dependent recruitment of Glis3 to primary cilia"
- Gary Yellen, Nathalie Agar: "Mass spectrometry metabolomics in brain slice with time- and cell-type-resolution"
- Darren Higgins, Marcia Goldberg, Jonathan Kagan, Eric Rubin, Michael Starnbach: "Bacterial Pathogenesis Initiative at Harvard: host-pathogen interactions at barrier surfaces"
- Gerhard Wagner, William Shi: "DNA-corralled nanodiscs for studies of large membrane proteins and their complexes"
- Andrew Kruse, Debora Marks, David Rudner: "Exit from dromancy: the molecular mechanisms underlying spore germination"
- Richard Frank, Thomas McGuire: TBD
- Corey Harwell, Wei-Chung Lee: "Hedgehog signaling mediated neuron-astrocyte crosstalk during cortical circuit assembly"
- Lee Rubin, Isaac Kohane: "Combining iPSC biology and electroic health records to personalize treatments for neurological disorders"
- Gordon Fishell, Steve McCarroll: "Gene regulatory network reconstruction using single-cell RNA sequencing"
- Marc Kirschner, Fernando Camargo: "A dynamic understanding of YAP activity uncouples its cell autonomous vs. non-autonomous effects in vitro and in vivo"
- Isaac Chiu, Stephen Liberles: "Neural control of infection responses and sickness behavior"
- Isaac Chiu: "Botulinum neurotoxins to treat bacterial infections"
- Joe Loparo, Johannes Walter: "The mechanism of pathway choice in DNA double strand break repair"
- Christopher Harvey, David Ginty: "Contribution of peripheral mechanoreceptor subtypes to the functional organization of somatosensory cortex"
- David Ginty: "Targeting peripheral somatosensory neurons to improve tactile and behavior phenotypes in ASD"