Anthony (Tony) Gaca, PhD

Anthony (Tony) Gaca, PhD

Ophthalmology
Microbial Pathogenesis Research
Gilmore Lab
Anthony (Tony) Gaca, PhD

Anthony (Tony) was raised in Grand Rapids, MI and completed his B.S. in Microbiology at Michigan State University in 2008. In 2014, Tony completed his Ph.D. at the University of Rochester. His doctoral research focused on defining the physiological contributions and transcriptional hierarchy under the control of nucleotide second messenger (p)ppGpp in Enterococcus faecalis. Following his graduation, he spent an additional year at the University of Rochester characterizing the enzymatic function of small (p)ppGpp synthase of E. faecalis leading to the discovery of a new regulatory nucleotide. Tony joined the laboratory of Dr. Michael Gilmore in the summer of 2015 and is working to (i) understand how rapid expansion of the enterococcal genome, associated with the emergence of multidrug resistance, broadly impacts fitness and (ii) identify antagonistic interactions among enterococci that can serve as new therapeutic approaches for preventing and limiting colonization by multidrug resistant lineages. His areas of expertise include: bacterial metabolism and stress tolerance, cloning and strain construction, protein expression and purification, anaerobic cell culture, and comparative genomics.

Contact Information

Department of Ophthalmology
Massachusetts Eye and Ear Infirmary
243 Charles St., Rm. C703
Boston, MA, 02114
p: (617) 573-3980

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