Miguel Gonzalez, MD, PhD

Miguel Gonzalez, MD, PhD

Ophthalmology
Cornea Research
Keratoprosthesis Group/Dohlman Lab
Miguel Gonzalez, MD, PhD

Dr Gonzalez is a clinician-scientist currently working in the Keratoprosthesis Group (Dohlman´s lab) at the Schepens Eye Research Institute and Mass Eye and Ear, Harvard Medical School. For 11 years, he worked as a researcher at the Tissue Engineering Group of the University of Granada, focusing his research on the construction of an artificial human cornea applying tissue engineering techniques, obtaining his PhD Cum Laude in 2011. His approach to generate a human artificial cornea was based on the generation of different types of artificial matrixes or scaffolds: fibrin-agarose scaffolds, decellularized porcine corneas and plastic-compressed collagen scaffolds. Dr Gonzalez was the coordinator and principal investigator for a multi-centric phase II clinical trial for the evaluation of artificial human corneas based on fibrin-agarose biomaterials with corneal cultured cells after carrying out the preclinical research. At the same time, he continued the experimental development of a new model of human corneal constructs based on decellularized porcine corneas that were recellularized with human corneal cells afterwards. Moreover, Dr Gonzalez established a collaboration with the University College of London for developing corneal substitutes based on multilayered plastic-compressed collagen scaffolds. The quality of work undertaken is demonstrated by multiple publications in high-impact international journals (J Cell Physiol, J Tissue Eng Regen Med, Exp Eye Res, Cornea, Invest Ophthalmol Vis Sci, etc.), as well as numerous scientific prizes awarded such as the MIT Technology Review - Innovators Under 35 Award or the Discovery Channel - Born To Be Discovery Award. Additionally, he carried out a successful training in medicine and ophthalmology, receiving the Pareja Yebenes’ prize for best student together with other awards such as the Sanitas and Barclays awards for the best Spanish and Andalusian residents, and the Arruga Award (from the Spanish Society of Ophthalmogy) to the best Spanish ophthalmologist under 40. In addition, his international and national experience in prestigious research centres (King´s College of London, Loyola University of Chicago, Spanish National Cancer Research Center, Columbia University, University College of London, Moorfields Eye Hospital, etc.) has established his scientific reputation. Furthermore, he has taught undergraduate and postgraduate courses at the University of Granada, together with teaching and mentoring to residents and research fellows. Moreover, he was the Spanish representative in the European Project “Joining Forces in Corneal Regeneration Research”. At present,  Dr Gonzalez is collaborating with Jing Kong´s group at MIT developing new materials and new designs for the Boston keratoprosthesis that could improve the biocompatibility and biointegration into corneal tissue.

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