Mohamed Ismail Ashrafali, PhD

Mohamed Ismail Ashrafali, PhD

Ophthalmology
Cornea Research
Chodosh Lab
Mohamed Ismail Ashrafali, PhD

Our focus is to study the evolution of human adenoviruses associated with epidemic keratoconjunctivitis- a severe eye infection. We employ phylogenetics, recombination detection tools and in silico structural predictions for genetic characterization of novel adenoviruses. To study the differential viral gene regulation, I am mapping transcription factors occupancy- across the genome by chromatin Immunoprecipitation and high throughput sequencing (ChIP-Seq). I am also studying adenovirus interactome by Affinity purification and Mass spectrometry methods. Studying viral DNA sensors and immune evasion strategies are my other current interests.

I enjoy food, music and travelling ;)

Contact Information

Howe Chodosh Laboratory
Massachusetts Eye and Ear Infirmary
Harvard Medical School
Boston, MA 02114

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