C9ORF72

Principal Investigator: Tim Miller, MD PhD

Disease: ALS

Project Duration: 6 months

Primary Aim(s):

  • Aim 1: Identify 60 C9ORF72ALS subjects
  • Aim 2: Determine C9ORF72 hexanucleotide repeat expansion size in all subjects
  • Aim 3: Define ALS disease course in C9ORF72 subjects
  • Aim 4: Determine to what degree the disease course correlates with expansion size
  • Aim 5: Collect biomarker samples including blood and CSF.

How CIB accelerates this project:

CIB operates as the data coordination core.
Platforms used: NeuroBANK™, NeuroGUID