Olfactory Deficits in Neurological Disease

Principal Investigator: Mark W. Albers, M.D. Ph.D.

Disease: Neurological Disease

Project Duration: 

Primary Aim(s):

  • Examine olfactory function in preclinical subjects or individuals with neurological diseases such as Probable Alzheimer’s Disease (PRAD), Frontotemporal Dementias (FTD), and Dementia with Lewy Bodies (DLB) that are part of the Longitudinal Research Cohort of the Massachusetts Alzheimer’s Disease Research Center, or are being treated by neurologists in the Memory Disorders or Movements Disorders Clinics at MGH.
  • Examine individuals with Amyotrophic Lateral Sclerosis (ALS) that are part of the Neurological Clinical Research Institute (NCRI) at MGH. Specifically, we will assess odor perception, odor identification, episodic olfactory memory, and olfactory affective reactivity (e.g. responsiveness to pleasant vs. unpleasant odor stimuli) using the OLFACT olfactometer (Osmic Enterprises). 

How NeuroBANKTM accelerates this project: