ssDNA-ssDNA pairing, dsDNA-dsDNA pairing, and RecA family protein mediated homologous recombination all involve self-assembly because free energetically favorable interactions form structures from less complex parts.


Efraim Feinstein’s PhD thesis considered several self-assembling systems, including the folding of a string of charged beads.


Single molecule measurements of the adhesion of uropathogenic Escherichia coli to mannose also revealed useful strategies for optimizing self-assembly., as did studies of the folding of strings of charged beads. The work on the uropathogenic bacteria and the charged beads were done in collaboration with the Whitesides group.