D. Branch Moody, MD
Dr. Moody is the TBRU co-Principal Investigator, the director of the Metabolomics Core and Lead investigator of Project 3.
The Moody laboratory studies the human immune response to M. tuberculosis and the molecular basis of tuberculosis pathogenesis. Our central goals are to understand how CD1 antigen presenting molecules display mycobacterial lipids to human T cells and the role of T cells in host response to infection. Certain mycobacterial lipids that trigger host response also promote virulence of M. tuberculosis so we seek to identify new lipid components in the mycobacterial cell wall.
Working as part of the the NIAID’s Tuberculosis Research Unit, the Moody laboratory will seek to identify mycobacterial molecules and T cell responses that will be useful to develop new rapid tests for tuberculosis infection in humans.