Beware the "long s"
The most frequent colonial-era convention you will encounter is likely the "long s," the letterform that looks a lot like a lowercase f.
This was practiced throughout the colonial period and beyond. Here are two examples from 1820:
|perhaps to Laziness|
|been lost by sickness.|
Common “misspellings” and writing conventions
You do not need to correct or modernize mispellings or general contractions and abbreviations.