We propose a method for detecting bipartite entanglement in a many-body mixed state based on estimating moments of the partially transposed density matrix. The estimates are obtained by performing local random measurements on the state, followed by post-processing using the classical shadows framework. Our method can be applied to any quantum system with single-qubit control. We provide a detailed analysis of the required number of experimental runs, and demonstrate the protocol using existing experimental data [Brydges et al, Science 364, 260 (2019)].

We discuss monitoring the time evolution of an analog quantum simulator via a quantum non-demolition (QND) coupling to an auxiliary `clock' qubit. The QND variable of interest is the `energy' of the quantum many-body system, represented by the Hamiltonian of the quantum simulator. We describe a physical implementation of the underlying QND Hamiltonian for Rydberg atoms trapped in tweezer arrays using laser dressing schemes for a broad class of spin models. As an application, we discuss a quantum protocol for measuring the spectral form factor of quantum many-body systems, where the aim is to identify signatures of ergodic vs. non-ergodic dynamics, which we illustrate for disordered 1D Heisenberg and Floquet spin models on Rydberg platforms. Our results also provide the physical ingredients for running quantum phase estimation protocols for measurement of energies, and preparation of energy eigenstates for a specified spectral resolution on an analog quantum simulator.

We design dipolar quantum many-body Hamiltonians that will facilitate the realization of exotic quantum phases under the current experimental conditions achieved for polar molecules and magnetic atoms with large dipolar moments. The main idea is to modulate both two-body dipolar interactions and single-body potential barriers on a spatial scale of tens of nanometers to strongly enhance energy scales of engineered many-body systems. This new scheme greatly relaxes the requirement for low temperatures necessary for observing new quantum phases, especially in comparison to Hubbard Hamiltonians for regular optical lattices. For polar molecules, our approach builds on the use of microwave fields to couple rotational energy eigenstates in static electric fields with strong gradients. We illustrate this approach by demonstrating the orientation switching on the nanoscale for the induced electric dipole moment of a polar molecule. This configuration leads to the formation of interface bound states of fermionic molecules with binding energies far exceeding typical energy scales in current experiments. While the concepts are developed for polar molecules, many of the present ideas can be readily carried over to atoms with magnetic dipolar interactions.

Motivated by the outstanding challenge of realizing lowerature states of quantum matter in synthetic materials, we propose and study an experimentally feasible protocol for preparing topological states such as Chern insulators. By definition, such (nonsymmetry protected) topological phases cannot be attained without going through a phase transition in a closed system, largely preventing their preparation in coherent dynamics. To overcome this fundamental caveat, we propose to couple the target system to a conjugate system, so as to prepare a symmetry protected topological phase in an extended system by intermittently breaking the protecting symmetry. Finally, the decoupled conjugate system is discarded, thus projecting onto the desired topological state in the target system. By construction, this protocol may be immediately generalized to the class of invertible topological phases, characterized by the existence of an inverse topological order. We illustrate our findings with microscopic simulations on an experimentally realistic Chern insulator model of ultracold fermionic atoms in a driven spin-dependent hexagonal optical lattice.