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Gaudet Lab
Department of Molecular and Cellular Biology
Harvard University

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  • nramp_980_550

    Inward-facing structure of transition metal transporter

    Our group studies the Nramp family of transition metal transporters, and recently determined this inward-facing structure

  • pic1

    Clustered protocadherins involved in neuronal patterning form antiparallel dimers

    We study the evolution, structure and assembly of clustered protocadherins, which are involved in neuronal self avoidance.

  • Our recent BBA Biomembranes review highlights how these analyses are powerful tools in studies of membrane proteins

    We use sequence coevolution analyses in our studies

    Our recent BBA Biomembranes review highlights how these analyses are powerful tools in studies of membrane proteins

  • Gaudet Lab

    Gaudet Lab Members

  • Nramp Conformations

    Conformations of an Nramp-family transition metal transporter

    Our new structures illustrate the three principal conformations of an Nramp transporter.

Lab News!

Brenda Chiang is graduating!

May 30, 2019
Congratulations to senior thesis writer Brenda! Today is Commencement Day!

Rachelle named HGWISE Mentor of the Year!

May 24, 2019
Congratulations Rachelle - see more on the award here!

Congratulations to Sriram Srikant!

May 22, 2019
who successfully defended his PhD thesis today, a joint adventure with the Murray lab!

Elizabeth receives QBio Student Fellowship!

April 25, 2019
Congratulations to Graduate Student Elizabeth May on her fellowship!

Elizabeth's work out in a cheRxiv preprint!

April 18, 2019
Her structure of inhibitor-bound NNMT, part of a collaboration with the Shair lab, is now available in chemRxiv.

Aaron and Christina's paper on Nramp conformations

February 8, 2019
is now out in eLife, identifying substrate pathways. Summary here!

Rocio and Jeff's paper on frog toxins

December 27, 2018
and their effect on bacterial channels, out in JGP. Collaboration with the French Lab in Calgary!

Jack and Anna's manuscript out in bioRxiv

December 11, 2018
on clustered protocadherin specificity - collaboration with Marks Lab!
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