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Gaudet Lab
Department of Molecular and Cellular Biology
Harvard University

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  • nramp_980_550

    Inward-facing structure of transition metal transporter

    Our group studies the Nramp family of transition metal transporters, and recently determined this inward-facing structure

  • pic1

    Clustered protocadherins involved in neuronal patterning form antiparallel dimers

    We study the evolution, structure and assembly of clustered protocadherins, which are involved in neuronal self avoidance.

  • Our recent BBA Biomembranes review highlights how these analyses are powerful tools in studies of membrane proteins

    We use sequence coevolution analyses in our studies

    Our recent BBA Biomembranes review highlights how these analyses are powerful tools in studies of membrane proteins

  • Picture of Gaudet Lab Members

    Gaudet Lab Members

    https://projects.iq.harvard.edu/gaudetlab/people

  • Nramp Conformations

    Conformations of an Nramp-family transition metal transporter

    Our new structures illustrate the three principal conformations of an Nramp transporter.

Lab News!

New paper on TRPV2 modulation by cannabinoids with lab alum Ute Hellmich

December 10, 2022
A collaboration with the Zygmunt lab, out in Nature Communications.

José's review on prodrug-activating peptidases published

November 8, 2022
in Biochimie. Find it here!

Rachelle featured in documentary series "Les Ambassadrices"

October 22, 2022
View here if you are in Canada. Associated podcast available here. 

José's structural analyses of the ClbP peptidase are published!

October 17, 2022
In Nature Chemical Biology - summary and links here!

Sam Berry wins poster award!

September 20, 2022
At the Annual Harvard Biophysics PhD Program Retreat!

New preprint from Shamayeeta

September 9, 2022
on metal binding and transport by Nramps. Read here!

Elizabeth received Simmons Award!

September 6, 2022
Funding for microscope use at the HCBI! Congrats!

Postdoc Sanket Walujkar receives Simons postdoc award!

September 1, 2022
from the Harvard NSF-Simons Center!
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