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Gaudet Lab
Department of Molecular and Cellular Biology
Harvard University

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  • nramp_980_550

    Inward-facing structure of transition metal transporter

    Our group studies the Nramp family of transition metal transporters, and recently determined this inward-facing structure

  • pic1

    Clustered protocadherins involved in neuronal patterning form antiparallel dimers

    We study the evolution, structure and assembly of clustered protocadherins, which are involved in neuronal self avoidance.

  • Our recent BBA Biomembranes review highlights how these analyses are powerful tools in studies of membrane proteins

    We use sequence coevolution analyses in our studies

    Our recent BBA Biomembranes review highlights how these analyses are powerful tools in studies of membrane proteins

  • Picture of Gaudet Lab Members

    Gaudet Lab Members

    https://projects.iq.harvard.edu/gaudetlab/people

  • Nramp Conformations

    Conformations of an Nramp-family transition metal transporter

    Our new structures illustrate the three principal conformations of an Nramp transporter.

Lab News!

Welcoming Amber Wei, first-year undergraduate!

January 6, 2022
Amber is joining our lab this spring!

First-year undergraduate Janny Liao joins the lab!

October 12, 2021
Welcome to the team, Janny!

New NRDD review on TRP channel drug discovery

October 9, 2021
With structural comparisons of TRP channels, ligand binding sites and disease-causing missense mutations. More here!

JMB special issue on transporters is out!

August 6, 2021
Issue co-edited by Rachelle - includes our review on Nramps.

Welcome to Summer Interns Emily and Tammie!

June 14, 2021
Emily Villalpando is an MCO SROH intern from UC Riverside, and Tammie Tam is a QBIO REU intern from UC Davis. Welcome!

Welcome to our newest Harvard undergraduate, Jorge Guerra!

June 7, 2021
Jorge is joining us as a PRISE Fellow this summer!

Gerardo Zavala awarded an NSF Graduate Research Fellowship!

May 26, 2021
Congratulations!

Serin awarded Fulbright Teaching Assistanship!

May 26, 2021
She will be teaching English in Taiwan next year! Read more here.
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